MAPK7 anticorps (pThr219, pTyr221) (Cy7)

N° du produit ABIN1409844

Cet anticorps anti-MAPK7 est un anticorps Lapin Polyclonal détectant MAPK7 dans IF (cc), IF (p) et FACS. Adapté pour Souris.

Aperçu rapide pour MAPK7 anticorps (pThr219, pTyr221) (Cy7) (ABIN1409844)

Antigène: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK7 est conjugé à/à la Cy7

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)

Détail du produit anti-MAPK7 anticorps (Cy7)

Épitope: pThr219, pTyr221

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human ERK5 around the phosphorylation site of Thr219 + Tyr221

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MAPK7

Antigène: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Autre désignation: ERK5 +

Sujet:

Synonyms: ERK5 phospho Thr219 + Tyr221, ERK5 phospho Thr219 + Tyr221, Big MAP kinase 1, BMK 1, BMK 1 kinase, BMK-1, BMK1, BMK1 Kinase, EC 2.7.11.24, ERK 4, ERK 5, ERK-5, ERK4, ERK5, Extracellular Signal Regulated Kinase 5, Extracellular signal-regulated kinase 5, MAP kinase 7, MAPK 7, MAPK7, Mitogen Activated Protein Kinase 7, Mitogen-activated protein kinase 7, MK07_HUMAN,

Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling