Metabotropic Glutamate Receptor 3 anticorps (AA 365-460) (HRP)

N° du produit ABIN1412540

L’anticorps Lapin Polyclonal anti-Metabotropic Glutamate Receptor 3 a été validé pour WB et ELISA. Il convient pour détecter Metabotropic Glutamate Receptor 3 dans des échantillons de Souris.

Aperçu rapide pour Metabotropic Glutamate Receptor 3 anticorps (AA 365-460) (HRP) (ABIN1412540)

Antigène: Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Metabotropic Glutamate Receptor 3 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA

Détail du produit anti-Metabotropic Glutamate Receptor 3 anticorps (HRP)

Épitope: AA 365-460

Réactivité croisée: Souris

Homologie: Human,Rat,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Metabotropic Glutamate Receptor 3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Metabotropic Glutamate Receptor 3

Antigène: Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))

Autre désignation: MGLUR3

Sujet:

Synonyms: G protein coupled receptor family C group 1 member C, GLUR 3, GLUR3, GLUR3, Glutamate metabotropic receptor 3, Glutamate receptor metabotropic 3, GPRC1C, GRM 3, GRM3, GRM3_HUMAN, Metabotropic glutamate receptor 3, Metabotropic glutamate receptor 3 precursor, mGlu 3, MGlu3, MGlu3, MGLUR 3, MGLUR3.

Background: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.

Pathways: cAMP Metabolic Process, Synaptic Membrane