GABRQ anticorps (PE)

N° du produit ABIN1429640

L’anticorps Lapin Polyclonal anti-GABRQ a été validé pour FACS. Il convient pour détecter GABRQ dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GABRQ anticorps (PE) (ABIN1429640)

Antigène: GABRQ (gamma-aminobutyric Acid (GABA) Receptor, theta (GABRQ))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GABRQ est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-GABRQ anticorps (PE)

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GABRQ/GABA A Receptor ta

Isotype: IgG

Information d'application

Indications d'application: FCM(1:20-100)

Commentaires:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at 4°C

Date de péremption: 12 months

Détails sur GABRQ

Antigène: GABRQ (gamma-aminobutyric Acid (GABA) Receptor, theta (GABRQ))

Autre désignation: Gabrq/Gaba A Receptor theta

Sujet:

Gamma-aminobutyric acid type A (GABAA) receptors mediate inhibitory neurotransmission in the mammalian central nervous system. The receptor exists as a pentameric ion channel composed by heteromeric combinations of alpha, beta, gamma, delta, epsilon, theta, or pi subunits. Only specific subunit combinations produce viable receptors, while others never translocate to the cell surface from the ER where they are synthesized, and subsequently degraded. The theta subunit forms a receptor in combination with alpha3 subunits in monoaminergic cell groups. These receptors, found especially in the septum, preoptic areas, hypothalamic nuclei, amygdala and thalamus, likely have unique pharmacological properties linked to their expression in this particular cell type and not cholinergic cell groups, and may play a role in opiate withdrawl symptoms.

Subcellular location: Extracellular

Synonyms: gamma aminobutyric acid GABA receptor, theta, Gamma aminobutyric acid receptor theta subunit precursor, gamma aminobutyric acid receptor, theta, THETA, GBRT_HUMAN.