ABI1 anticorps

N° du produit ABIN1449186

Cet anticorps anti-ABI1 est un anticorps Souris Monoclonal détectant ABI1 dans WB, IP et IHC (p). Adapté pour Humain, Souris et Hamster.

Aperçu rapide pour ABI1 anticorps (ABIN1449186)

Antigène: ABI1 (Abl-Interactor 1 (ABI1))

Reactivité: Humain, Souris, Hamster

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ABI1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1B9

Détail du produit anti-ABI1 anticorps

Specificité: This antibody reacts with Abi-1.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Hamster

Purification: Protein A agarose

Immunogène: Human recombinant Abi-1 expressed in E. coli

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Upon receipt, store (in aliqouts) at -20 °C.

Détails sur ABI1

Antigène: ABI1 (Abl-Interactor 1 (ABI1))

Autre désignation: ABI1 / SSH3BP1

Sujet: Abl interactor (Abi) proteins are c-Abl-binding proteins that bind to both the Src homology 3 (SH3) domain and the C-terminal proline-rich regions of Abl kinase through dual SH3-PXXP interactions. Two highly related genes, abi-1 and abi-2, were cloned. In addition to the interaction with Abl kinase, Abi proteins also interact with other signaling molecules. Recently, it has been reported that Abi-1 dramatically promoted c-Abl-mediated tyrosine (Tyr296) phosphorylation of Mena [mammalian homologue of Drosophila Enabled (Ena)] by interacting with both proteins.Synonyms: Abelson interactor 1, Abi-1, Abl interactor 1, Abl-binding protein 4, AblBP4, Eps8 SH3 domain-binding protein, Nap1-binding protein, Spectrin SH3 domain-binding protein 1, Spectrin binding protein, e3B1

Poids moléculaire: 65 kDa

ID gène: 10006

NCBI Accession: NP_001012768

UniProt: Q8IZP0

Pathways: Signalisation RTK, Response to Water Deprivation, ER-Nucleus Signaling