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Mesothelin anticorps
MSLN
Reactivité: Souris
FACS
Hôte: Rat
Monoclonal
B35
unconjugated
N° du produit ABIN1449246
Détail du produit anti-Mesothelin anticorps
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Antigène
Voir toutes Mesothelin (MSLN) Anticorps
Mesothelin (MSLN)
Reactivité
Toutes les réactivités sur Mesothelin Anticorps
Souris
Hôte
Toutes les hôtes sur Mesothelin Anticorps
Rat
Clonalité
Toutes les clonalités sur Mesothelin Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers Mesothelin Anticorps
Cet anticorp Mesothelin est non-conjugé
Application
Tous les applications à travers Mesothelin Anticorps.
Flow Cytometry (FACS)
Specificité
This antibody reacts with mouse mesothelin.
Purification
Protein G agarose
Immunogène
Murine hemangioblast-like cell line LO
Clone
B35
Isotype
IgG2a
Top Product
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
1.0 mg/mL
Buffer
PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
Agent conservateur
Without preservative
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
-20 °C
Stockage commentaire
Upon receipt, store (in aliqouts) at -20 °C.
Détails sur Mesothelin
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Antigène
Mesothelin (MSLN)
Autre désignation
Mesothelin (MSLN Produits )
Synonymes
anticorps MPF, anticorps SMRP, anticorps MSLN, anticorps mesothelin, anticorps MSLN, anticorps Msln, anticorps LOC611363, anticorps LOC100524016
Sujet
Mesothelin (MSLN) is a GPI-linked cell surface glycoprotein expressed in the mesothelial lining of the body cavities and in mullerian duct epithelium related cancer cells (ovarian, pancreatic cancer, mesothelioma). Both human and mouse mesothelin bind to ovarian cancer antigen CA125/MUC16 with high affinity, mediating cell attachment in vitro , suggesting that mesothelin may facilitate ovarian cancer metastasis.Synonyms: CAK1 antigen, MPF, MSLN, Pre-pro-megakaryocyte-potentiating factor
ID gène
56047
NCBI Accession
NP_061345
UniProt
Q61468
Pathways
EGFR Signaling Pathway , Positive Regulation of Peptide Hormone Secretion , Intracellular Steroid Hormone Receptor Signaling Pathway , Steroid Hormone Mediated Signaling Pathway , Carbohydrate Homeostasis , cAMP Metabolic Process , Regulation of G-Protein Coupled Receptor Protein Signaling , Positive Regulation of Endopeptidase Activity , Regulation of Carbohydrate Metabolic Process
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