Mesothelin anticorps

N° du produit ABIN1449246

Cet anticorps anti-Mesothelin Monoclonal Rat (Clone B35) (ABIN1449246) détecte spécifiquement Mesothelin dans FACS. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour Mesothelin anticorps (ABIN1449246)

Antigène: Mesothelin (MSLN)

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Mesothelin est non-conjugé

Application: Flow Cytometry (FACS)

Clone: B35

Détail du produit anti-Mesothelin anticorps

Specificité: This antibody reacts with mouse mesothelin.

Purification: Protein G agarose

Immunogène: Murine hemangioblast-like cell line LO

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Upon receipt, store (in aliqouts) at -20 °C.

Détails sur Mesothelin

Antigène: Mesothelin (MSLN)

Autre désignation: Mesothelin

Sujet: Mesothelin (MSLN) is a GPI-linked cell surface glycoprotein expressed in the mesothelial lining of the body cavities and in mullerian duct epithelium related cancer cells (ovarian, pancreatic cancer, mesothelioma). Both human and mouse mesothelin bind to ovarian cancer antigen CA125/MUC16 with high affinity, mediating cell attachment in vitro , suggesting that mesothelin may facilitate ovarian cancer metastasis.Synonyms: CAK1 antigen, MPF, MSLN, Pre-pro-megakaryocyte-potentiating factor

ID gène: 56047

NCBI Accession: NP_061345

UniProt: Q61468

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process