ATG14 anticorps (Middle Region)

N° du produit ABIN1449976

Cet anticorps Lapin Polyclonal détecte spécifiquement ATG14 dans WB, IF et EIA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ATG14 anticorps (Middle Region) (ABIN1449976)

Antigène: ATG14 (ATG14 Autophagy Related 14 (ATG14))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG14 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-ATG14 anticorps

Épitope: Middle Region

Purification: Affinity chromatography purified via peptide column

Immunogène: ATG14 antibody was raised against an 18 amino acid synthetic peptide near the center of Human ATG14

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ATG14

Antigène: ATG14 (ATG14 Autophagy Related 14 (ATG14))

Autre désignation: ATG14 / Barkor

Sujet: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein ATG1. ATG14 is a subunit of a class III phosphatidylinositol (PtdIns) 3-kinase complex that targets the complex to the endoplasmic reticulum, the site of autophagosome formation.Synonyms: Atg14L, Beclin 1-associated autophagy-related key regulator, KIAA0831

Poids moléculaire: 54 kDa

ID gène: 22863

NCBI Accession: NP_055739

Pathways: Autophagy