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ATG14 anticorps (ATG14 Autophagy Related 14) AA 1-492 (Biotin) Primary Antibody

ATG14 Reactivité: Humain ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN7145340
$328.90
Plus shipping costs $45.00
100 μg
local_shipping Destination: Etats-Unis
Envoi sous 10 à 13 jours ouvrables
  • Antigène Voir toutes ATG14 Anticorps
    ATG14
    Épitope
    • 10
    • 8
    • 7
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-492
    Reactivité
    • 52
    • 17
    • 9
    • 1
    Humain
    Hôte
    • 44
    • 8
    Lapin
    Clonalité
    • 44
    • 8
    Polyclonal
    Conjugué
    • 23
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp ATG14 est conjugé à/à la Biotin
    Application
    • 37
    • 27
    • 21
    • 10
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Beclin 1-associated autophagy-related key regulator protein (1-492AA)
    Isotype
    IgG
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    ATG14
    Autre désignation
    ATG14 (ATG14 Produits)
    Synonymes
    ATG14L, BARKOR, KIAA0831, 4832427M01, Atg14L, D14Ertd114e, D14Ertd436e, RGD1304610, autophagy related 14, ATG14, Atg14
    Sujet

    Background: Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1 (PubMed:18843052, PubMed:19050071). Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine (PubMed:19270696, PubMed:20713597). Promotes BECN1 translocation from the trans-Golgi network to autophagosomes (PubMed:20713597). Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1 (PubMed:23878393). Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK (PubMed:23878393). Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion (PubMed:25686604). Modulates the hepatic lipid metabolism (By similarity).

    Aliases: 4832427M01 antibody, ATG14 antibody, Atg14L antibody, Autophagy-related protein 14-like protein antibody, BAKOR_HUMAN antibody, Barkor antibody, Beclin 1-associated autophagy-related key regulator antibody, D14Ertd114e antibody, D14Ertd436e antibody, KIAA0831 antibody, mCG_6911 antibody

    UniProt
    Q6ZNE5
    Pathways
    Autophagy
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