WIPI1 anticorps (C-Term)

N° du produit ABIN1449977

L’anticorps anti-WIPI1 Polyclonal Lapin est utilisé pour la détection de WIPI1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IF et EIA.

Aperçu rapide pour WIPI1 anticorps (C-Term) (ABIN1449977)

Antigène: WIPI1 (WD Repeat Domain, phosphoinositide Interacting 1 (WIPI1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WIPI1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-WIPI1 anticorps

Épitope: C-Term

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid synthetic peptide near the carboxy terminus of Human WIPI1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur WIPI1

Antigène: WIPI1 (WD Repeat Domain, phosphoinositide Interacting 1 (WIPI1))

Autre désignation: WIPI-1

Sujet: WIPI1 (WD repeat domain, phosphoinositide interacting-1), also known as WIPI1, ATG18 or WIPI49, is thought to play a role in autophagy and may regulate protein trafficking in certain recycling pathways. It contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles and the trans-Golgi network. It is ubiquitously expressed with highest expression in heart, testis, placenta, pancreas and skeletal muscle. WIPI1 is upregulated in a variety of tumors, suggesting a role in carcinogenesis.Synonyms: Atg18 protein homolog, WD repeat domain phosphoinositide-interacting protein 1, WD40 repeat protein interacting with phosphoinositides of 49 kDa, WIPI1, WIPI49

Poids moléculaire: 49 kDa

ID gène: 55062

NCBI Accession: NP_060453

Pathways: Nuclear Hormone Receptor Binding, ER-Nucleus Signaling