DISP1 anticorps (N-Term)

N° du produit ABIN1450084

Détail du produit anti-DISP1 anticorps

Antigène: DISP1 (Dispatched Homolog 1 (DISP1))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DISP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse

Purification: Affinity chromatography purified via peptide column

Immunogène: A 16 amino acid synthetic peptide near the amino terminus of human DISP1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur DISP1

Antigène: DISP1 (Dispatched Homolog 1 (DISP1))

Autre désignation: DISP1 / DISPA (DISP1 Produits)

Synonymes: anticorps DISP1, anticorps DISPA, anticorps 1190008H24Rik, anticorps DispA, anticorps con, anticorps zgc:111866, anticorps dispatched, anticorps dispatched RND transporter family member 1, anticorps dispatched homolog 1 (Drosophila), anticorps CpipJ_CPIJ008642, anticorps DISP1, anticorps Disp1, anticorps disp1

Sujet: DISP1 is the mammalian homolog of the Drosophila Dispatched segment-polarity gene and a key regulator of the Hedgehog (Hh) signaling pathway during embryonic development. DISP1 is required to move Shh from site of synthesis during embryogenesis, mutations in the gene result in lethality at mid-gestation and prevents specification of ventral cell types in the neural tube. Recent results have shown that DISP1 mediates the basolateral secretion of Shh and regulates growth of mammalian long bones through the control of Ihh.Synonyms: Protein dispatched homolog 1

ID gène: 84976

NCBI Accession: NP_116279

Pathways: Signalisation Hedgehog