CD33 anticorps (Middle Region)

N° du produit ABIN1450097

L’anticorps Lapin Polyclonal anti-CD33 a été validé pour WB et EIA. Il convient pour détecter CD33 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CD33 anticorps (Middle Region) (ABIN1450097)

Antigène: CD33

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD33 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-CD33 anticorps

Épitope: Middle Region

Purification: Affinity chromatography purified via peptide column

Immunogène: CD33 antibody was raised against a 14 amino acid synthetic peptide near the center of human CD33.

Isotype: IgG

Information d'application

Indications d'application: CD33 antibody can be used for detection of CD33 by Western blot at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur CD33

Antigène: CD33

Autre désignation: CD33 / SIGLEC3

Sujet: CD33 is a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family that is highly expressed on myeloid progenitor cells. Assessment of CD33 expression is of great importance in the immunodiagnosis of acute leukemia, allowing distinction between myeloid and lymphoid origin, as CD33 is generally restricted to the myelomonocytic lineage. CD33 can associate with the protein-tyrosine phosphatases SHP-1 and SHP-2 and thus could modulate downstream signaling events associated with cell activation. Common variants of CD33 have been found to be associated with late-onset Alzheimer's disease.Synonyms: Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, Siglec-3, gp67

ID gène: 945

NCBI Accession: NP_001763