SETMAR anticorps (AA 350-400)

N° du produit ABIN1451979

Cet anticorps anti-SETMAR Polyclonal Lapin (ABIN1451979) détecte spécifiquement SETMAR dans ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SETMAR anticorps (AA 350-400) (ABIN1451979)

Antigène: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SETMAR est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-SETMAR anticorps

Épitope: AA 350-400

Fonction: SETMAR Antibody

Specificité: SETMAR Polyclonal Antibody detects endogenous levels of SETMAR protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human SETMAR. AA range:350-400

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur SETMAR

Antigène: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Autre désignation: SETMAR

Sujet:

Synonyms: SETMAR, Histone-lysine N-methyltransferase SETMAR, SET domain and mariner transposase fusion gene-containing protein, HsMar1, Metnase

Background: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],

Gene Name: SETMAR

Protein Name: Histone-lysine N-methyltransferase SETMAR

Poids moléculaire: 76 kDa

ID gène: 6419

OMIM: 609834

UniProt: Q53H47

Pathways: Positive Regulation of Response to DNA Damage Stimulus