HIF3A anticorps (AA 305-354)
Aperçu rapide pour HIF3A anticorps (AA 305-354) (ABIN1453401)
Antigène
Voir toutes HIF3A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 305-354
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Fonction
- HIF-3α Antibody
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Specificité
- HIF-3α Polyclonal Antibody detects endogenous levels of HIF-3α protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- The antiserum was produced against synthesized peptide derived from human HIF-3alpha. AA range:305-354
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
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Autre désignation
- HIF-3Alpha
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Sujet
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Synonyms: Hypoxia-inducible factor 3-alpha, HIF-3-alpha, HIF3-alpha, Basic-helix-loop-helix-PAS protein MOP7, Class E basic helix-loop-helix protein 17, bHLHe17, HIF3-alpha-1, Inhibitory PAS domain protein, IPAS, Member of PAS protein 7, PAS domain-c
Background: hypoxia inducible factor 3 alpha subunit(HIF3A) Homo sapiens The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011],
Gene Name: HIF3A
Protein Name: Hypoxia-inducible factor 3-alpha
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Poids moléculaire
- 72 kDa
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ID gène
- 64344
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OMIM
- 609976
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UniProt
- Q66K72
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Pathways
- L'effet Warburg
Antigène
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