SOCS2 anticorps (AA 18-67)

N° du produit ABIN1453938

Cet anticorps anti-SOCS2 Polyclonal Lapin (ABIN1453938) détecte spécifiquement SOCS2 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour SOCS2 anticorps (AA 18-67) (ABIN1453938)

Antigène: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SOCS2 anticorps

Épitope: AA 18-67

Fonction: SOCS-2 Antibody

Specificité: SOCS-2 Polyclonal Antibody detects endogenous levels of SOCS-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human SOCS-2. AA range:18-67

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur SOCS2

Antigène: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Autre désignation: SOCS-2

Sujet:

Synonyms: SOCS2, CIS2, SSI2, STATI2, Suppressor of cytokine signaling 2, SOCS-2, Cytokine-inducible SH2 protein 2, CIS-2, STAT-induced STAT inhibitor 2, SSI-2

Background: This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor.The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has

Gene Name: SOCS2

Protein Name: Suppressor of cytokine signaling 2

Poids moléculaire: 22 kDa

ID gène: 8835

OMIM: 605117

UniProt: O14508

Pathways: Signalistation JAK/STAT, Response to Growth Hormone Stimulus