Rhodopsin anticorps (pSer334)

N° du produit ABIN1531388

Cet anticorps anti-Rhodopsin Polyclonal Lapin (ABIN1531388) détecte spécifiquement Rhodopsin dans IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Rhodopsin anticorps (pSer334) (ABIN1531388)

Antigène: Rhodopsin (RHO)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Rhodopsin est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-Rhodopsin anticorps

Épitope: AA 299-348, pSer334

Fonction: Rhodopsin (phospho Ser334) Antibody

Specificité: Phospho-Rhodopsin (S334) Polyclonal Antibody detects endogenous levels of Rhodopsin protein only when phosphorylated at S334.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Rhodopsin around the phosphorylation site of Ser334. AA range:299-348

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Rhodopsin

Antigène: Rhodopsin (RHO)

Autre désignation: Rhodopsin

Classe de substances: Chemical

Sujet:

Synonyms: RHO, OPN2, Rhodopsin, Opsin-2

Background: Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25 % of total cases, approximately 30 % of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness. [provided by RefSeq, Jul 2008],

Gene Name: RHO

Protein Name: Rhodopsin

Poids moléculaire: 39 kDa

ID gène: 6010

OMIM: 180380

UniProt: P08100

Pathways: Signalisation WNT, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction