Cyclin E2 anticorps (pThr392)

N° du produit ABIN1531565

L’anticorps anti-Cyclin E2 Polyclonal Lapin est utilisé pour la détection de Cyclin E2 dans des échantillons de Humain et Souris. Il a été validé pour IF et ELISA.

Aperçu rapide pour Cyclin E2 anticorps (pThr392) (ABIN1531565)

Antigène: Cyclin E2 (CCNE2)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin E2 est non-conjugé

Application: Immunofluorescence (IF), ELISA

Détail du produit anti-Cyclin E2 anticorps

Épitope: AA 355-404, pThr392

Fonction: Cyclin E2 (phospho Thr392) Antibody

Specificité: Phospho-Cyclin E2 (T392) Polyclonal Antibody detects endogenous levels of Cyclin E2 protein only when phosphorylated at T392.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Cyclin E2 around the phosphorylation site of Thr392. AA range:355-404

Isotype: IgG

Information d'application

Indications d'application: IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Cyclin E2

Antigène: Cyclin E2 (CCNE2)

Autre désignation: Cyclin E2

Sujet:

Synonyms: CCNE2, G1/S-specific cyclin-E2

Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [provided by RefSeq, Jul 2008],

Gene Name: CCNE2

Protein Name: G1/S-specific cyclin-E2

Poids moléculaire: 46 kDa

ID gène: 9134

OMIM: 603775

UniProt: O96020

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases