CDK9 anticorps (pThr186)

N° du produit ABIN1531647

Cet anticorps anti-CDK9 Polyclonal Lapin (ABIN1531647) détecte spécifiquement CDK9 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CDK9 anticorps (pThr186) (ABIN1531647)

Antigène: CDK9 (Cyclin-Dependent Kinase 9 (CDK9))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK9 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CDK9 anticorps

Épitope: AA 152-201, pThr186

Fonction: Cdk9 (phospho Thr186) Antibody

Specificité: Phospho-Cdk9 (T186) Polyclonal Antibody detects endogenous levels of Cdk9 protein only when phosphorylated at T186.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human CDK9 around the phosphorylation site of Thr186. AA range:152-201

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CDK9

Antigène: CDK9 (Cyclin-Dependent Kinase 9 (CDK9))

Autre désignation: CDK9

Sujet:

Synonyms: CDK9, CDC2L4, TAK, Cyclin-dependent kinase 9, C-2K, Cell division cycle 2-like protein kinase 4, Cell division protein kinase 9, Serine/threonine-protein kinase PITALRE, Tat-associated kinase complex catalytic subunit

Background: cyclin dependent kinase 9(CDK9) Homo sapiens The protein encoded byThis gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008],

Gene Name: CDK9

Protein Name: Cyclin-dependent kinase 9

Poids moléculaire: 42 kDa

ID gène: 1025

OMIM: 603251

UniProt: P50750

Pathways: Cycle Cellulaire