Aurora Kinase B anticorps (pTyr12)

N° du produit ABIN1531706

L’anticorps anti-Aurora Kinase B Polyclonal Lapin est utilisé pour la détection de Aurora Kinase B dans des échantillons de Humain, Souris et Rat. Il a été validé pour IHC, WB, ELISA et IF.

Aperçu rapide pour Aurora Kinase B anticorps (pTyr12) (ABIN1531706)

Antigène: Aurora Kinase B (AURKB)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aurora Kinase B est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-Aurora Kinase B anticorps

Épitope: AA 1-50, pTyr12

Fonction: ARK-2 (phospho Tyr12) Antibody

Specificité: Phospho-ARK-2 (Y12) Polyclonal Antibody detects endogenous levels of ARK-2 protein only when phosphorylated at Y12.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human AurB around the phosphorylation site of Tyr12. AA range:1-50

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Aurora Kinase B

Antigène: Aurora Kinase B (AURKB)

Autre désignation: AurB

Sujet:

Synonyms: AURKB, AIK2, AIM1, AIRK2, ARK2, STK1, STK12, STK5, Aurora kinase B, Aurora 1, Aurora- and IPL1-like midbody-associated protein 1, AIM-1, Aurora/IPL1-related kinase 2, ARK-2, Aurora-related kinase 2, STK-1, Serine/threonine-protein kinase 12

Background: This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015],

Gene Name: AURKB

Protein Name: Aurora kinase B,Aurora B

Poids moléculaire: 39 kDa

ID gène: 9212

OMIM: 604970

UniProt: Q96GD4

Pathways: TCR Signaling, Cycle Cellulaire, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades