AXL anticorps (pTyr691)

N° du produit ABIN1532036

Cet anticorps anti-AXL Polyclonal Lapin (ABIN1532036) détecte spécifiquement AXL dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour AXL anticorps (pTyr691) (ABIN1532036)

Antigène: AXL (AXL Receptor tyrosine Kinase (AXL))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AXL est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-AXL anticorps

Épitope: AA 657-706, pTyr691

Fonction: Axl (phospho Tyr691) Antibody

Specificité: Phospho-Axl (Y691) Polyclonal Antibody detects endogenous levels of Axl protein only when phosphorylated at Y691.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human AXL around the phosphorylation site of Tyr691. AA range:657-706

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur AXL

Antigène: AXL (AXL Receptor tyrosine Kinase (AXL))

Autre désignation: AXL

Sujet:

Synonyms: AXL, UFO, Tyrosine-protein kinase receptor UFO, AXL oncogene

Background: The protein encoded byThis gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],

Gene Name: AXL UFO

Protein Name: Tyrosine-protein kinase receptor UFO

Poids moléculaire: 97 kDa

ID gène: 558

OMIM: 109135

UniProt: P30530

Pathways: Signalisation RTK, Cellular Response to Molecule of Bacterial Origin