BRCA1 anticorps (pSer1457)

N° du produit ABIN1532128

Détail du produit anti-BRCA1 anticorps

Antigène: BRCA1 (Breast Cancer 1 (BRCA1))

Épitope: AA 1423-1472, pSer1457

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRCA1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité:

BRCA1 (Phospho-Ser1457) Antibody detects endogenous levels of BRCA1 only when phosphorylated at Ser1457.

PhosphorylationH:S1457

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human BRCA1 around the phosphorylation site of Ser1457.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500~1:1000 ELISA: 1:1000

Commentaires:

Unigene-Number: Hs.194143 (NCBI Gene Symbol: BRCA1)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable at -20°C for at least 1 year.

Date de péremption: 12 months

Détails sur BRCA1

Antigène: BRCA1 (Breast Cancer 1 (BRCA1))

Autre désignation: BRCA1 (BRCA1 Produits)

Synonymes: anticorps BRCAI, anticorps BRCC1, anticorps BROVCA1, anticorps IRIS, anticorps PNCA4, anticorps PPP1R53, anticorps PSCP, anticorps RNF53, anticorps iris, anticorps pscp, anticorps brcai, anticorps brcc1, anticorps rnf53, anticorps brca1, anticorps BRCA1, anticorps LOC100224649, anticorps BRCA1, DNA repair associated, anticorps breast cancer 1, anticorps breast cancer 1, early onset, anticorps breast cancer 1 L homeolog, anticorps BRCA1, anticorps brca1, anticorps LOC755086, anticorps Brca1, anticorps brca1.L

Sujet:

Synonyms: BRCA1, Breast cancer type 1 susceptibility protein, familial breast/ovarian cancer gene 1

NCBI Gene Symbol: BRCA1

Poids moléculaire: 207 kDa

ID gène: 672

OMIM: 113705

UniProt: P38398

Pathways: Cycle Cellulaire, Réparation de l'ADN, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus