Lamin A/C anticorps (pSer22)

N° du produit ABIN1532183

Cet anticorps Lapin Polyclonal détecte spécifiquement Lamin A/C dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat et a été mentionné dans 3+ publications.

Aperçu rapide pour Lamin A/C anticorps (pSer22) (ABIN1532183)

Antigène: Lamin A/C (LMNA)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lamin A/C est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Lamin A/C anticorps

Épitope: AA 2-51, pSer22

Specificité:

Lamin A (Phospho-Ser22) Antibody detects endogenous levels of Lamin A only when phosphorylated at Ser22.

PhosphorylationH:S22 M:S22 R:S22

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Lamin A around the phosphorylation site of Ser22.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500~1:1000 ELISA: 1:1000

Commentaires:

Unigene-Number: Hs.594444 (NCBI Gene Symbol: LMNA)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable at -20°C for at least 1 year.

Date de péremption: 12 months

Références pour anticorps anti-Lamin A/C (ABIN1532183)

Häge, Sonntag, Svrlanska, Borst, Stilp, Horsch, Müller, Kropff, Milbradt, Stamminger, Schlötzer-Schrehardt, Marschall: "Phenotypical Characterization of the Nuclear Egress of Recombinant Cytomegaloviruses Reveals Defective Replication upon ORF-UL50 Deletion but Not pUL50 Phosphosite Mutation." dans: Viruses, Vol. 13, Issue 2, (2021) (PubMed).

Schütz, Steingruber, Socher, Müller, Wagner, Kögel, Sticht, Marschall: "Functional Relevance of the Interaction between Human Cyclins and the Cytomegalovirus-Encoded CDK-Like Protein Kinase pUL97." dans: Viruses, Vol. 13, Issue 7, (2021) (PubMed).

Häge, Büscher, Pakulska, Hahn, Adrait, Krauter, Borst, Schlötzer-Schrehardt, Couté, Plachter, Marschall: "The Complex Regulatory Role of Cytomegalovirus Nuclear Egress Protein pUL50 in the Production of Infectious Virus." dans: Cells, Vol. 10, Issue 11, (2021) (PubMed).

Détails sur Lamin A/C

Antigène: Lamin A/C (LMNA)

Autre désignation: Lamin A

Sujet:

Synonyms: 70 kDa lamin, LAMA, LMN1, LMNA

NCBI Gene Symbol: LMNA

Poids moléculaire: 74 kDa

ID gène: 4000

OMIM: 115200

UniProt: P02545

Pathways: Apoptose, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus