SAG anticorps (AA 369-418)

N° du produit ABIN1532317

Cet anticorps anti-SAG Polyclonal Lapin (ABIN1532317) détecte spécifiquement SAG dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain et Singe.

Aperçu rapide pour SAG anticorps (AA 369-418) (ABIN1532317)

Antigène: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Reactivité: Humain, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAG est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-SAG anticorps

Épitope: AA 369-418

Fonction: Arrestin-β-1 Antibody

Specificité: Arrestin-β-1 Polyclonal Antibody detects endogenous levels of Arrestin-β-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Arrestin 1. AA range:369-418

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur SAG

Antigène: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Autre désignation: Arrestin 1

Sujet:

Synonyms: ARRB1, ARR1, Beta-arrestin-1, Arrestin beta-1

Background: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011],

Gene Name: ARRB1

Protein Name: Beta-arrestin-1

Poids moléculaire: 47 kDa

ID gène: 408

OMIM: 107940

UniProt: P49407

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling