SAG anticorps (AA 210-290)

N° du produit ABIN7227368

L’anticorps anti-SAG Polyclonal Lapin est utilisé pour la détection de SAG dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour SAG anticorps (AA 210-290) (ABIN7227368)

Antigène: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAG est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-SAG anticorps

Épitope: AA 210-290

Fonction: Rabbit Anti-ARRS Polyclonal Antibody

Specificité: The antibody detects endogenous levels of ARRS protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human ARRS protein at AA range: 210-290

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SAG

Antigène: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Autre désignation: ARRS

Sujet: S-arrestin, 48 kDa protein, Retinal S-antigen, Rod photoreceptor arrestinSAG (S-Antigen Visual Arrestin) is a Protein Coding gene. Diseases associated with SAG include Oguchi Disease-1 and Retinitis Pigmentosa 47. Among its related pathways are Phototransduction and Visual Cycle in Retinal Rods. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in SAG have been associated with Oguchi disease, a rare autosomal recessive form of night blindness.

Poids moléculaire: 44kD

ID gène: 6295

UniProt: P10523

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling