MITF anticorps (AA 151-200)
Aperçu rapide pour MITF anticorps (AA 151-200) (ABIN1532362)
Antigène
Voir toutes MITF AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 151-200
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Fonction
- MITF Antibody
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Specificité
- MITF Polyclonal Antibody detects endogenous levels of MITF protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human MITF. AA range:151-200
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- MITF (Microphthalmia-Associated Transcription Factor (MITF))
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Autre désignation
- MITF
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Sujet
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Synonyms: MITF, BHLHE32, Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32, bHLHe32
Background: This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
Gene Name: MITF
Protein Name: Microphthalmia-associated transcription factor
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Poids moléculaire
- 58 kDa
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ID gène
- 4286
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OMIM
- 103470
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UniProt
- O75030
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Pathways
- Chromatin Binding
Antigène
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