CD4 anticorps (AA 401-450)
Aperçu rapide pour CD4 anticorps (AA 401-450) (ABIN1532559)
Antigène
Voir toutes CD4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 401-450
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Fonction
- CD4 Antibody
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Specificité
- CD4 Polyclonal Antibody detects endogenous levels of CD4 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human CD4. AA range:401-450
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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: "Th17-cells in atopic dermatitis stimulate orthodontic root resorption." dans: Oral diseases, (2013) (PubMed).
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- CD4
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Autre désignation
- CD4
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Sujet
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Synonyms: CD4, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD antigen CD4
Background: This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010],
Gene Name: CD4
Protein Name: T-cell surface glycoprotein CD4
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Poids moléculaire
- 51 kDa
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ID gène
- 920
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OMIM
- 186940
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UniProt
- P01730
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Pathways
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
Antigène
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