IFNAR1 anticorps (AA 436-485)

N° du produit ABIN1532631

Cet anticorps Lapin Polyclonal détecte spécifiquement IFNAR1 dans IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour IFNAR1 anticorps (AA 436-485) (ABIN1532631)

Antigène: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFNAR1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-IFNAR1 anticorps

Épitope: AA 436-485

Fonction: IFN-α/βRα Antibody

Specificité: IFN-α/βRα Polyclonal Antibody detects endogenous levels of IFN-α/βRα protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Interferon-alpha/beta Receptor alpha chain. AA range:436-485

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur IFNAR1

Antigène: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Autre désignation: Interferon-alpha/beta Receptor alpha Chain

Sujet:

Synonyms: IFNAR1, IFNAR, Interferon alpha/beta receptor 1, IFN-R-1, IFN-alpha/beta receptor 1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, CRF2-1, Type I interferon receptor 1

Background: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. [provided by RefSeq, Jul 2008],

Gene Name: IFNAR1

Protein Name: Interferon alpha/beta receptor 1

Poids moléculaire: 63 kDa

ID gène: 3454

OMIM: 107450

UniProt: P17181

Pathways: Signalistation JAK/STAT, Hepatitis C