TYK2 anticorps (AA 1020-1069)

N° du produit ABIN1533032

Cet anticorps anti-TYK2 Polyclonal Lapin (ABIN1533032) détecte spécifiquement TYK2 dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Singe.

Aperçu rapide pour TYK2 anticorps (AA 1020-1069) (ABIN1533032)

Antigène: TYK2 (Tyrosine Kinase 2 (TYK2))

Reactivité: Humain, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TYK2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-TYK2 anticorps

Épitope: AA 1020-1069

Fonction: Tyk 2 Antibody

Specificité: Tyk 2 Polyclonal Antibody detects endogenous levels of Tyk 2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human TYK2. AA range:1020-1069

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TYK2

Antigène: TYK2 (Tyrosine Kinase 2 (TYK2))

Autre désignation: TYK2

Sujet:

Synonyms: TYK2, Non-receptor tyrosine-protein kinase TYK2

Background: tyrosine kinase 2(TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008],

Gene Name: TYK2

Protein Name: Non-receptor tyrosine-protein kinase TYK2

Poids moléculaire: 133 kDa

ID gène: 7297

OMIM: 176941

UniProt: P29597

Pathways: Signalistation JAK/STAT, Hepatitis C