Glucagon anticorps (AA 61-110)
Aperçu rapide pour Glucagon anticorps (AA 61-110) (ABIN1533287)
Antigène
Voir toutes Glucagon (GCG) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 61-110
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Fonction
- GCG Antibody
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Specificité
- GCG Polyclonal Antibody detects endogenous levels of GCG protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human Glucagon. AA range:61-110
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- Glucagon (GCG)
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Autre désignation
- Glucagon
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Sujet
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Synonyms: GCG, Glucagon
Background: The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008],
Gene Name: GCG
Protein Name: Glucagon
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Poids moléculaire
- 20 kDa
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ID gène
- 2641
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OMIM
- 138030
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UniProt
- P01275
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Pathways
- Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling
Antigène
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