GRM8 anticorps (AA 841-890)

N° du produit ABIN1533293

Cet anticorps Lapin Polyclonal détecte spécifiquement GRM8 dans WB, IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GRM8 anticorps (AA 841-890) (ABIN1533293)

Antigène: GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRM8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-GRM8 anticorps

Épitope: AA 841-890

Fonction: mGluR-8 Antibody

Specificité: MGluR-8 Polyclonal Antibody detects endogenous levels of mGluR-8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human mGluR8. AA range:841-890

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur GRM8

Antigène: GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))

Autre désignation: mGluR8

Sujet:

Synonyms: GRM8, GPRC1H, MGLUR8, Metabotropic glutamate receptor 8, mGluR8

Background: glutamate metabotropic receptor 8(GRM8) Homo sapiens L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been d

Gene Name: GRM8

Protein Name: Metabotropic glutamate receptor 8

Poids moléculaire: 101 kDa

ID gène: 2918

OMIM: 601116

UniProt: O00222

Pathways: cAMP Metabolic Process, Synaptic Membrane