PCNA anticorps (AA 61-110)

N° du produit ABIN1533376

L’anticorps anti-PCNA Polyclonal Lapin est utilisé pour la détection de PCNA dans des échantillons de Humain, Souris, Rat, Singe et Lapin. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour PCNA anticorps (AA 61-110) (ABIN1533376)

Antigène: PCNA (Proliferating Cell Nuclear Antigen (PCNA))

Reactivité: Humain, Souris, Rat, Singe, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCNA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-PCNA anticorps

Épitope: AA 61-110

Fonction: PCNA Antibody

Specificité: PCNA Polyclonal Antibody detects endogenous levels of PCNA protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human PCNA. AA range:61-110

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:100-500,IF ICC 1:100-500,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur PCNA

Antigène: PCNA (Proliferating Cell Nuclear Antigen (PCNA))

Autre désignation: PCNA

Sujet:

Synonyms: PCNA, Proliferating cell nuclear antigen, PCNA, Cyclin

Background: The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008],

Gene Name: PCNA

Protein Name: Proliferating cell nuclear antigen

Poids moléculaire: 28 kDa

ID gène: 5111

OMIM: 176740

UniProt: P12004

Pathways: Telomere Maintenance, Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy