DR4 anticorps (AA 401-450)

N° du produit ABIN1533474

Cet anticorps Lapin Polyclonal détecte spécifiquement DR4 dans WB, ELISA et IF. Il présente une réactivité avec des échantillons de Humain et Singe.

Aperçu rapide pour DR4 anticorps (AA 401-450) (ABIN1533474)

Antigène: DR4 (Drought-Repressed 4 Protein (DR4))

Reactivité: Humain, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DR4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-DR4 anticorps

Épitope: AA 401-450

Fonction: DR4 Antibody

Specificité: DR4 Polyclonal Antibody detects endogenous levels of DR4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human TNFRSF10A. AA range:401-450

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur DR4

Antigène: DR4 (Drought-Repressed 4 Protein (DR4))

Autre désignation: TR10A

Sujet:

Synonyms: TNFRSF10A, APO2, DR4, TRAILR1, Tumor necrosis factor receptor superfamily member 10A, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TRAIL receptor 1, TRAIL-R1, CD antigen CD261

Background: The protein encoded byThis gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008],

Gene Name: TNFRSF10A

Protein Name: Tumor necrosis factor receptor superfamily member 10A

Poids moléculaire: 50 kDa

ID gène: 8797

OMIM: 603611

UniProt: O00220

Pathways: Apoptose, Positive Regulation of Endopeptidase Activity