LMTK2 anticorps (AA 651-700)

N° du produit ABIN1533992

Cet anticorps anti-LMTK2 Polyclonal Lapin (ABIN1533992) détecte spécifiquement LMTK2 dans WB, IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour LMTK2 anticorps (AA 651-700) (ABIN1533992)

Antigène: LMTK2 (Lemur tyrosine Kinase 2 (LMTK2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LMTK2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-LMTK2 anticorps

Épitope: AA 651-700

Fonction: KPI-2 Antibody

Specificité: KPI-2 Polyclonal Antibody detects endogenous levels of KPI-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human LMTK2. AA range:651-700

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur LMTK2

Antigène: LMTK2 (Lemur tyrosine Kinase 2 (LMTK2))

Autre désignation: LMTK2

Sujet:

Synonyms: LMTK2, AATYK2, BREK, KIAA1079, KPI2, LMR2, Serine/threonine-protein kinase LMTK2, Apoptosis-associated tyrosine kinase 2, Brain-enriched kinase, hBREK, CDK5/p35-regulated kinase, CPRK, Kinase/phosphatase/inhibitor 2, Lemur tyrosine kinase 2

Background: The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis. [provided by RefSeq, Oct 2009],

Gene Name: LMTK2

Protein Name: Serine/threonine-protein kinase LMTK2

Poids moléculaire: 164 kDa

ID gène: 22853

OMIM: 610989

UniProt: Q8IWU2

Pathways: Signalisation RTK, Neurotrophin Signaling Pathway