TINF2 anticorps (AA 71-120)

N° du produit ABIN1534093

L’anticorps anti-TINF2 Polyclonal Lapin est utilisé pour la détection de TINF2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour TINF2 anticorps (AA 71-120) (ABIN1534093)

Antigène: TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TINF2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-TINF2 anticorps

Épitope: AA 71-120

Fonction: TIN2 Antibody

Specificité: TIN2 Polyclonal Antibody detects endogenous levels of TIN2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human TINF2. AA range:71-120

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TINF2

Antigène: TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))

Autre désignation: TINF2

Sujet:

Synonyms: TINF2, TIN2, TERF1-interacting nuclear factor 2, TRF1-interacting nuclear protein 2

Background: This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage.The protein encoded by this gene is a critical part of shelterin, it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome. [provided by RefSeq, Mar 2010],

Gene Name: TINF2

Protein Name: TERF1-interacting nuclear factor 2

Poids moléculaire: 50 kDa

ID gène: 26277

OMIM: 127550

UniProt: Q9BSI4

Pathways: Cycle Cellulaire, Telomere Maintenance, Regulation of Carbohydrate Metabolic Process