Cadherin-16 anticorps (AA 780-829)
Aperçu rapide pour Cadherin-16 anticorps (AA 780-829) (ABIN1534285)
Antigène
Voir toutes Cadherin-16 (CDH16) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 780-829
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Fonction
- Cadherin-16 Antibody
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Specificité
- Cadherin-16 Polyclonal Antibody detects endogenous levels of Cadherin-16 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human CDH16. AA range:780-829
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- Cadherin-16 (CDH16)
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Autre désignation
- CDH16
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Sujet
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Synonyms: CDH16, Cadherin-16, Kidney-specific cadherin, Ksp-cadherin
Background: This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011],
Gene Name: CDH16
Protein Name: Cadherin-16
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Poids moléculaire
- 89 kDa
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ID gène
- 1014
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OMIM
- 603118
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UniProt
- O75309
Antigène
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