CENPA anticorps (AA 11-60)
Aperçu rapide pour CENPA anticorps (AA 11-60) (ABIN1534330)
Antigène
Voir toutes CENPA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 11-60
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Fonction
- CENP-A Antibody
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Specificité
- CENP-A Polyclonal Antibody detects endogenous levels of CENP-A protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human CENPA. AA range:11-60
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Isotype
- IgG
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Indications d'application
- IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- CENPA (Centromere Protein A (CENPA))
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Autre désignation
- CENPA
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Sujet
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Synonyms: CENPA, Histone H3-like centromeric protein A, Centromere autoantigen A, Centromere protein A, CENP-A
Background: Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes.This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015],
Gene Name: CENPA
Protein Name: Histone H3-like centromeric protein A
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Poids moléculaire
- 15 kDa
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ID gène
- 1058
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OMIM
- 117139
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UniProt
- P49450
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Pathways
- Chromatin Binding, Maintenance of Protein Location
Antigène
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