MLH3 anticorps (AA 521-570)

N° du produit ABIN1534469

Cet anticorps anti-MLH3 Polyclonal Lapin (ABIN1534469) détecte spécifiquement MLH3 dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MLH3 anticorps (AA 521-570) (ABIN1534469)

Antigène: MLH3 (MutL Homolog 3 (MLH3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLH3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MLH3 anticorps

Épitope: AA 521-570

Fonction: MLH3 Antibody

Specificité: MLH3 Polyclonal Antibody detects endogenous levels of MLH3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human MLH3. AA range:521-570

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MLH3

Antigène: MLH3 (MutL Homolog 3 (MLH3))

Autre désignation: MLH3

Sujet:

Synonyms: MLH3, DNA mismatch repair protein Mlh3, MutL protein homolog 3

Background: This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination.The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008],

Gene Name: MLH3

Protein Name: DNA mismatch repair protein Mlh3

Poids moléculaire: 163 kDa

ID gène: 27030

OMIM: 114500

UniProt: Q9UHC1

Pathways: Chromatin Binding