POLE anticorps (AA 1261-1310)

N° du produit ABIN1534837

L’anticorps anti-POLE Polyclonal Lapin est utilisé pour la détection de POLE dans des échantillons de Humain et Rat. Il a été validé pour ELISA, IHC et IF.

Aperçu rapide pour POLE anticorps (AA 1261-1310) (ABIN1534837)

Antigène: POLE (Polymerase (DNA Directed), Epsilon, Catalytic Subunit (POLE))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLE est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-POLE anticorps

Épitope: AA 1261-1310

Fonction: DNA pol ε A Antibody

Specificité: DNA pol ε A Polyclonal Antibody detects endogenous levels of DNA pol ε A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human POLE1. AA range:1261-1310

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur POLE

Antigène: POLE (Polymerase (DNA Directed), Epsilon, Catalytic Subunit (POLE))

Autre désignation: POLE1

Sujet:

Synonyms: POLE, POLE1, DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A

Background: DNA polymerase epsilon, catalytic subunit(POLE) Homo sapiens This gene encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in this gene have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature. [provided by RefSeq, Sep 2013],

Gene Name: POLE

Protein Name: DNA polymerase epsilon catalytic subunit A

Poids moléculaire: 261 kDa

ID gène: 5426

OMIM: 174762

UniProt: Q07864

Pathways: Telomere Maintenance, Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA