MBTPS2 anticorps (AA 301-350)

N° du produit ABIN1535018

Cet anticorps anti-MBTPS2 Polyclonal Lapin (ABIN1535018) détecte spécifiquement MBTPS2 dans ELISA, WB, IF et IP. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MBTPS2 anticorps (AA 301-350) (ABIN1535018)

Antigène: MBTPS2 (Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBTPS2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit anti-MBTPS2 anticorps

Épitope: AA 301-350

Fonction: S2P Antibody

Specificité: S2P Polyclonal Antibody detects endogenous levels of S2P protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human MBTPS2. AA range:301-350

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MBTPS2

Antigène: MBTPS2 (Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2))

Autre désignation: MBTPS2

Sujet:

Synonyms: MBTPS2, S2P, Membrane-bound transcription factor site-2 protease, Endopeptidase S2P, Sterol regulatory element-binding proteins intramembrane protease, SREBPs intramembrane protease

Background: This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome), IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009],

Gene Name: MBTPS2

Protein Name: Membrane-bound transcription factor site-2 protease

Poids moléculaire: 57 kDa

ID gène: 51360

OMIM: 300294

UniProt: O43462

Pathways: ER-Nucleus Signaling