NOX3 anticorps (AA 287-336)
Aperçu rapide pour NOX3 anticorps (AA 287-336) (ABIN1535076)
Antigène
Voir toutes NOX3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 287-336
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Fonction
- Nox3 Antibody
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Specificité
- Nox3 Polyclonal Antibody detects endogenous levels of Nox3 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human NOX3. AA range:287-336
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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: "A long-term high-fat diet increases oxidative stress, mitochondrial damage and apoptosis in the inner ear of D-galactose-induced aging rats." dans: Hearing research, Vol. 287, Issue 1-2, pp. 15-24, (2012) (PubMed).
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- NOX3 (NADPH Oxidase 3 (NOX3))
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Autre désignation
- NOX3
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Sujet
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Synonyms: NOX3, MOX2, NADPH oxidase 3, Mitogenic oxidase 2, MOX-2, gp91phox homolog 3, GP91-3
Background: This gene encodes a member of the NOX family of NADPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membrane. The ROS generated by family members have been implicated in numerous biological functions including host defense, posttranlational processing of proteins, cellular signaling, regulation of gene expression, and cell differentiation.The protein encoded by this gene is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.[provided by RefSeq, May 2009],
Gene Name: NOX3
Protein Name: NADPH oxidase 3
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Poids moléculaire
- 64 kDa
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ID gène
- 50508
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OMIM
- 607105
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UniProt
- Q9HBY0
Antigène
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