PIK3R5 anticorps (AA 695-744)
Aperçu rapide pour PIK3R5 anticorps (AA 695-744) (ABIN1535170)
Antigène
Voir toutes PIK3R5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 695-744
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Fonction
- PI 3-kinase p101 Antibody
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Specificité
- PI 3-kinase p101 Polyclonal Antibody detects endogenous levels of PI 3-kinase p101 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human PIK3R5. AA range:695-744
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- PIK3R5 (Phosphoinositide-3-Kinase, Regulatory Subunit 5 (PIK3R5))
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Autre désignation
- PIK3R5
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Sujet
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Synonyms: PIK3R5, Phosphoinositide 3-kinase regulatory subunit 5, PI3-kinase regulatory subunit 5, PI3-kinase p101 subunit, Phosphatidylinositol 4, 5-bisphosphate 3-kinase regulatory subunit, PtdIns-3-kinase regulatory subunit, Protein FOAP-2, PtdIns-
Background: Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis.This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. [provided by RefSeq, Oct 2011],
Gene Name: PIK3R5
Protein Name: Phosphoinositide 3-kinase regulatory subunit 5
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Poids moléculaire
- 97 kDa
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ID gène
- 23533
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OMIM
- 611317
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UniProt
- Q8WYR1
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Pathways
- Signalisation PI3K-Akt, Inositol Metabolic Process, Hepatitis C, VEGF Signaling
Antigène
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