FZD8 anticorps (AA 486-535)
Aperçu rapide pour FZD8 anticorps (AA 486-535) (ABIN1535685)
Antigène
Voir toutes FZD8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 486-535
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Fonction
- Frizzled-8 Antibody
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Specificité
- Frizzled-8 Polyclonal Antibody detects endogenous levels of Frizzled-8 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human FZD8. AA range:486-535
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- FZD8 (Frizzled Family Receptor 8 (FZD8))
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Autre désignation
- FZD8
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Sujet
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Synonyms: FZD8, Frizzled-8, Fz-8, hFz8
Background: frizzled class receptor 8(FZD8) Homo sapiens This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008],
Gene Name: FZD8
Protein Name: Frizzled-8
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Poids moléculaire
- 73 kDa
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ID gène
- 8325
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OMIM
- 606146
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UniProt
- Q9H461
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Pathways
- Signalisation WNT
Antigène
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