Metabotropic Glutamate Receptor 1 anticorps (AA 251-300)

N° du produit ABIN1535754

Cet anticorps Lapin Polyclonal détecte spécifiquement Metabotropic Glutamate Receptor 1 dans IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Metabotropic Glutamate Receptor 1 anticorps (AA 251-300) (ABIN1535754)

Antigène: Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Metabotropic Glutamate Receptor 1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-Metabotropic Glutamate Receptor 1 anticorps

Épitope: AA 251-300

Fonction: mGluR1 Antibody

Specificité: MGluR1 Polyclonal Antibody detects endogenous levels of mGluR1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human GRM1. AA range:251-300

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Metabotropic Glutamate Receptor 1

Antigène: Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

Autre désignation: GRM1

Sujet:

Synonyms: GRM1, GPRC1A, MGLUR1, Metabotropic glutamate receptor 1, mGluR1

Background: glutamate metabotropic receptor 1(GRM1) Homo sapiens This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013],

Gene Name: GRM1

Protein Name: Metabotropic glutamate receptor 1

Poids moléculaire: 132 kDa

ID gène: 2911

OMIM: 604473

UniProt: Q13255