Metabotropic Glutamate Receptor 1 anticorps (AA 387-486)

N° du produit ABIN5611175

Cet anticorps Souris Monoclonal détecte spécifiquement Metabotropic Glutamate Receptor 1 dans ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Metabotropic Glutamate Receptor 1 anticorps (AA 387-486) (ABIN5611175)

Antigène: Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Metabotropic Glutamate Receptor 1 est non-conjugé

Application: ELISA

Clone: 5E12D8

Détail du produit anti-Metabotropic Glutamate Receptor 1 anticorps

Épitope: AA 387-486

Fonction: GRM1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human GRM1 (AA: 387-486) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur Metabotropic Glutamate Receptor 1

Antigène: Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

Autre désignation: GRM1

Sujet: This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire: 132.4 kDa

ID gène: 2911