Caspase 7 anticorps (Cleaved-Ser199)

N° du produit ABIN1536085

L’anticorps anti-Caspase 7 Polyclonal Lapin est utilisé pour la détection de Caspase 7 dans des échantillons de Humain et Souris. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour Caspase 7 anticorps (Cleaved-Ser199) (ABIN1536085)

Antigène: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-Caspase 7 anticorps

Épitope: AA 180-229, Cleaved-Ser199

Fonction: Cleaved-Caspase-7 (S199) Antibody

Specificité: Cleaved-Caspase-7 (S199) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-7 protein resulting from cleavage adjacent to S199.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Caspase 7. AA range:180-229

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Caspase 7

Antigène: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Autre désignation: Caspase 7

Sujet:

Synonyms: CASP7, MCH3, Caspase-7, CASP-7, Apoptotic protease Mch-3, CMH-1, ICE-like apoptotic protease 3, ICE-LAP3

Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],

Gene Name: CASP7

Protein Name: Caspase7

Poids moléculaire: 20 kDa

ID gène: 840

OMIM: 601761

UniProt: P55210

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity