Septin 2 anticorps (C-Term)
Aperçu rapide pour Septin 2 anticorps (C-Term) (ABIN1537024)
Antigène
Voir toutes Septin 2 (SEPT2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 280-309, C-Term
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Homologie
- B, M, Rat
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This SEPT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 280-309 amino acids from the C-terminal region of human SEPT2.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000. WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- SEPT2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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Date de péremption
- 6 months
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- Septin 2 (SEPT2)
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Autre désignation
- SEPT2
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Sujet
- Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.
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Poids moléculaire
- 41487
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ID gène
- 4735
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NCBI Accession
- NP_001008491, NP_001008492, NP_004395, NP_006146
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UniProt
- Q15019
Antigène
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