GDF15 anticorps (AA 125-151)

N° du produit ABIN1537803

Cet anticorps anti-GDF15 est un anticorps Lapin Polyclonal détectant GDF15 dans WB. Adapté pour Humain.

Aperçu rapide pour GDF15 anticorps (AA 125-151) (ABIN1537803)

Antigène: GDF15 (Growth Differentiation Factor 15 (GDF15))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GDF15 est non-conjugé

Application: Western Blotting (WB)

Clone: RB39612

Détail du produit anti-GDF15 anticorps

Épitope: AA 125-151

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PDF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-151 amino acids from the Central region of human PDF.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: PDF Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur GDF15

Antigène: GDF15 (Growth Differentiation Factor 15 (GDF15))

Autre désignation: PDF

Sujet: Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides. In eubacteria, deformylation of nascent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a natural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRNAs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells.

Poids moléculaire: 27013

ID gène: 64146

NCBI Accession: NP_071736

UniProt: Q9HBH1

Pathways: SARS-CoV-2 Protein Interactome