desert Hedgehog anticorps (AA 195-223)

N° du produit ABIN1538035

Cet anticorps Lapin Polyclonal détecte spécifiquement desert Hedgehog dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour desert Hedgehog anticorps (AA 195-223) (ABIN1538035)

Antigène: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp desert Hedgehog est non-conjugé

Application: Western Blotting (WB)

Clone: RB39505

Détail du produit anti-desert Hedgehog anticorps

Épitope: AA 195-223

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This DHH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of human DHH.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: DHH Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur desert Hedgehog

Antigène: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Autre désignation: DHH

Classe de substances: Species

Sujet: This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved, the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.

Poids moléculaire: 43577

ID gène: 50846

NCBI Accession: NP_066382

UniProt: O43323

Pathways: Signalisation Hedgehog