TPP1 anticorps (N-Term)
Aperçu rapide pour TPP1 anticorps (N-Term) (ABIN1539423)
Antigène
Voir toutes TPP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 6-34, N-Term
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Homologie
- Pr
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This TPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human TPP1.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- TPP1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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Date de péremption
- 6 months
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- TPP1 (Tripeptidyl Peptidase I (TPP1))
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Autre désignation
- TPP1
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Sujet
- This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
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Poids moléculaire
- 61248
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ID gène
- 1200
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NCBI Accession
- NP_000382
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UniProt
- O14773
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Pathways
- Cycle Cellulaire, ER-Nucleus Signaling
Antigène
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