TBK1 anticorps (N-Term)

N° du produit ABIN1539557

Détail du produit anti-TBK1 anticorps

Antigène: TBK1 (TANK-Binding Kinase 1 (TBK1))

Épitope: AA 8-35, N-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TBK1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Mouse Tbk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-35 amino acids from the N-terminal region of mouse Tbk1.

Clone: RB37152

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Mouse Tbk1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur TBK1

Antigène: TBK1 (TANK-Binding Kinase 1 (TBK1))

Autre désignation: Tbk1 (TBK1 Produits)

Synonymes: anticorps nak, anticorps t2k, anticorps TBK1, anticorps wu:fk70c05, anticorps zgc:136548, anticorps NAK, anticorps T2K, anticorps 1200008B05Rik, anticorps AI462036, anticorps AW048562, anticorps TANK binding kinase 1 L homeolog, anticorps TANK binding kinase 1, anticorps TANK-binding kinase 1, anticorps tbk1.L, anticorps TBK1, anticorps tbk1, anticorps Tbk1

Sujet: Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response.

Poids moléculaire: 83425

ID gène: 56480

NCBI Accession: NP_062760

UniProt: Q9WUN2

Pathways: Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome