Tuberin anticorps

N° du produit ABIN1539797

L’anticorps anti-Tuberin Monoclonal produit chez le Souris a été validé pour WB et IF. Il convient pour la détection de Tuberin dans des échantillons provenant de Souris. }

Aperçu rapide pour Tuberin anticorps (ABIN1539797)

Antigène: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Tuberin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 249CT19-1-3

Détail du produit anti-Tuberin anticorps

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This TSC2 monoclonal antibody is generated from mouse immunized with TSC2 recombinant protein.

Isotype: IgG1 kappa

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: TSC2 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur Tuberin

Antigène: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Autre désignation: TSC2

Sujet: Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire: 200608

ID gène: 7249

NCBI Accession: NP_000539, NP_001070651, NP_001107854

UniProt: P49815

Pathways: Signalisation RTK, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus