Angiotensin I Converting Enzyme 1 anticorps (AA 1274-1306)

N° du produit ABIN1539969

Cet anticorps anti-Angiotensin I Converting Enzyme 1 est un anticorps Souris Monoclonal détectant Angiotensin I Converting Enzyme 1 dans WB. Adapté pour Souris.

Aperçu rapide pour Angiotensin I Converting Enzyme 1 anticorps (AA 1274-1306) (ABIN1539969)

Antigène: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Angiotensin I Converting Enzyme 1 est non-conjugé

Application: Western Blotting (WB)

Clone: 536CT24-1-3

Détail du produit anti-Angiotensin I Converting Enzyme 1 anticorps

Épitope: AA 1274-1306

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogène: This ACE antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 1274-1306 amino acids from human ACE.

Isotype: IgG2a

Information d'application

Indications d'application: WB: 1:500~16000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: ACE Antibody (Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur Angiotensin I Converting Enzyme 1

Antigène: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Autre désignation: ACE

Sujet: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.

Poids moléculaire: 149715

ID gène: 1636

NCBI Accession: NP_000780, NP_001171528, NP_690043

UniProt: P12821

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration